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KMID : 1036920150200020102
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Annals of Pediatric Endocrinology & Metabolism
2015 Volume.20 No. 2 p.102 ~ p.105
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Formula fed twin infants with recurrent hypocalcemic seizures with vitamin D deficient rickets and hyperphosphatemia
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Jo Byung-Wook
Shim Ye-Jee
Choi Jin-Hyeok
Kim Jun-Sik
Lee Hee-Joung
Kim Heung-Sik
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Abstract
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Vitamin D deficient rickets is generally known to occur in breast fed infants. And excessive phosphate ingestion is a main cause of late onset hypocalcemia in formula fed infants. Here we introduce 45-day-old formula fed hypocalcemic twins with recurrent seizure attacks. They were diagnosed as having both of vitamin D deficient rickets and hyperphosphatemia. Radiologic findings indicated mild rickets and the twins were treated with calcium and alfacalcidol. After 3-5 months of oral supplementation, medication was discontinued in both twins. They showed normal growth and calcium, phosphorus, and vitamin D levels during the 6-month follow-up period. Twins can be at risk for hypocalcemia because of their high risk of vitamin D deficiency, low birth weight, and premature birth. Therefore twin pregnant women need ingestion of sufficient vitamin D and calcium.
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KEYWORD
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Twins, Vitamin D deficiency, Hypocalcemia, Seizures, Rickets
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